Recognizing the Symptoms of Mesothelioma

Mesothelioma is a deadly form of cancer that affects people who have been exposed to asbestos. Asbestos is a naturally occurring mineral that was once mined and utilized in great quantities across the United States and worldwide. Commercial and industrial asbestos use peaked in the U.S. in the middle of the 20th century, but it had already become apparent that the mineral was causing serious health problems. The U.S. government began regulating asbestos in the 1970s based on its link to mesothelioma, lung cancer, asbestosis, respiratory disorders and other serious health problems. Unfortunately, the widespread regulation of asbestos came too late for many people who had already been exposed.

Asbestos fibers are easily inhaled and ingested. Once they are introduced into the body, they may become embedded in the mesothelium, the lining of the organs and body cavities. They may become lodged in the pleura (lining of the lungs), peritoneum (lining of the abdomen) or pericardium (lining of the heart). The body cannot easily expel asbestos fibers that have become embedded in these areas, and they may remain there for many years, causing irritation, inflammation and the eventual development of cancerous cells. This form of cancer is called mesothelioma.

As with any form of cancer and most medical conditions, an early diagnosis is crucial if a patient is to have the best chance at survival. Unfortunately the symptoms can be difficult to recognize because of their similarity to symptoms of common medical conditions and mesothelioma's long latency period. Chronic cough, chest pain, abdominal pain and other similar ailments may be shrugged off as symptoms of minor illnesses. They may be quite mild at first. A patient may not even consider mesothelioma as a potential issue because so much time has elapsed since asbestos exposure occurred. According to one study, it took patients as long as 39 months from the initial presentation of symptoms to receive appropriate treatment.

The majority of mesothelioma patients are diagnosed with pleural mesothelioma, which affects the lining of the lungs and chest cavity. The most common symptoms of this condition include shortness of breath, chest pain, chronic cough, limited or reduced chest expansion, fatigue and weight loss. A patient may also experience chest pain or painful breathing, fever or night sweats and may cough up blood.

Symptoms of peritoneal mesothelioma, which affects the lining of the abdominal organs and cavity, include abdominal pain and swelling, changes in bowel habits or function, weight loss, fatigue, lumps under the skin of the abdomen, anemia, nausea, night sweats and fever.

Pericardial mesothelioma is extremely rare. This form of cancer affects the lining of the heart. Some reported symptoms include irregular heartbeat, chest pain, chronic cough, difficulty breathing, heart murmur, fatigue, night sweats and fever. Additional symptoms may be reported as more patients are diagnosed and data is collected.

It may take approximately 20 to 50 years from exposure to asbestos minerals for a patient to experience symptoms of mesothelioma and seek medical treatment. These symptoms may vary somewhat depending on the type of mesothelioma as well as the patient's age, overall health and preexisting medical conditions, if any. If you notice these symptoms and have a history of asbestos exposure, it is important to seek medical attention as soon as possible - even if you feel that you are not seriously ill. A chronic cough or shortness of breath may be signs that cancerous cells have developed in your lung tissue or the lining of your chest or lungs. Tell your doctor what symptoms you are experiencing and inform him or her of your history with asbestos. Even if you did not work directly with or around the mineral, you may have experienced secondary exposure from a family member. Full disclosure will help your doctor determine what tests need to be run and whether to refer you to a specialist to confirm the diagnosis.

Article Source: http://EzineArticles.com/7218419


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Non-Small Cell Lung Cancer (Stage 1) - Symptoms, Diagnosis, Stages and Treatment

Symptoms

Stage 1 non-small cell lung cancer (NSCLC) may be present in a sufferer without showing any signs or symptoms. It is usually diagnosed when a doctor orders a patient to take a chest X-ray which is often associated with another illness. Symptoms may include: a persistent cough (smoker's cough), shortness of breath, wheezing, and recurrent bronchitis or pneumonia. At this early stage, other symptoms are not usually present in a sufferer.

Diagnosis

Stage 1 NSCLC is localized (contained within the lungs) and has not spread to the lymph nodes or other organs in the body.

Stages

- 1 The cancer is localized within the lungs but has not yet spread to the lymph nodes.

- 1A (the tumor is 3 cm or less in diameter).

- 1B (the tumor is between 3-5 cm in diameter).

These stages may also be described with a system called TNM (T = tumor size, N = nodes, and M = metastasis [spread of cancer]). Example:

- 1A (T1N0M0) Meaning that the tumor is less than 3 cm (T1), with no nodes (N0), and no metastasis (M0).

- 1B (T2N0M0) Meaning that the tumor is greater than 3 cm (T2), with no nodes (N0), and no metastasis (M0).

Treatment

Surgery is usually considered as the primary option for Stage 1 lung cancer treatment where removal of the tumor may be done via various different techniques. These techniques may include: segmentectomy (removal of a small segment of the lung), lobectomy (removal of the lobe of the lung), or pneumonectomy (removal of the entire lung).

Video-assisted thoracoscopic surgery (VATS) may be used when either the location of the tumor is difficult to reach using traditional surgery, or when the general health of the patient is not at its best and considered that the patient would not be able to tolerate a full surgical procedure. VATS is also less intrusive on the patient than traditional surgery.

If the cancer is considered to be inoperable, radiation therapy may be used to treat it.

Stereotactic body radiosurgery (SBRS) is one treatment that may be considered. This is where the patient is first immobilized in a frame to stop any movement, then computer imaging techniques are used to identify precisely where the cancerous cells are. These cells are then in turn destroyed by being given high dosages of radiation.

Conventional radiation therapy's are not usually recommended with Stage 1A lung cancer, although with Stage 1B, adjuvant chemotherapy (chemotherapy used after surgery to kill off any remaining cancerous cells) may be offered.

Article Source: http://EzineArticles.com/7223728


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'Panoramic View' of Lung Cancer Gained From Latest Trials

Results from three recent genome-sequencing trials have provided a revolutionary insight into the deadly disease.

Lung cancer is responsible for more deaths than any other form of the disease. Fewer than 20% of the 1.6 million cases diagnosed across the globe every year are still alive five years later.

The trend in new studies focuses on personalised treatment. Genome-sequencing trials are used to match the best possible treatment to the specific genetic make up of a patient's tumours.

In the latest trials, researchers analysed tumour tissue samples from 183 patients suffering from lung adenocarcinomas, 178 suffering from lung squamous cell carcinomas and drilled-down studies of 17 tumours from smokers and non-smokers.

Author of two of the studies, Ramaswamy Govindan from the Washington University School of Medicine in St Louis, said:

"For the first time, instead of looking through a keyhole we are getting a penthouse panoramic view,"

He added that previous studies had already looked more closely at personalised treatment but focused on a small number of genes. In contrast, the recent studies gleaned data across an entire genome.

Professor Govindan, who specialises in Medical Oncology believes that these kinds of "cataloguing studies" will revolutionise the way lung cancer clinical trials are designed. Instead of huge, expensive trials that feature a diverse collection of mutations, smaller studies will laser-down into patients' tumours according to their specific mutation. Medical experts are expecting this tailored therapy to be more beneficial for patients suffering from cancer.

The advances of such studies are clear - generic treatments tend to have a far greater number of side-effects as they are simply designed to kill any rapidly dividing cells rather than only attacking the ones spreading the disease. Furthermore, data from the targeted studies not only forms the basis of new treatments, they can cast light on those ones already on the market.

Article Source: http://EzineArticles.com/7303704


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What Is Asbestos?

The set of silicate minerals which is commercially used for their desirable physical properties is known as Asbestos. The word asbestos comes from the ancient Greek meaning "unquenchable" or "inextinguishable". The term asbestos is traceable to Roman naturalist Pliny the Elder's manuscript Natural History, and his use of the term asbestinon, meaning "unquenchable".

Asbestos became increasingly popular among manufacturers and builders in the late 19th century because of its sound absorption, average tensile strength, its resistance to fire, heat, electrical and chemical damage, and affordability.

It was used in such applications as electrical insulation for hot plate wiring and in building insulation. When asbestos is used for its resistance to fire or heat, the fibers are often mixed with cement (resulting in fiber cement) or woven into fabric or mats.

Breathing in asbestos fibers can cause asbestos, pleural disease, lung cancer and mesothelioma.

The risk of contracting these diseases increases with the number of fibers inhaled and the risk of lung cancer from inhaling asbestos fibers is also greater if you smoke. The symptoms of these diseases do not usually appear until about 20 to 30 years after the first exposure to asbestos.

Where to find asbestos

Some of areas in your home where you may find asbestos include:

· eaves, soffits, gutters and rainwater fall pipes

· fire blankets

· garage and shed roofs

· linings for walls, ceilings and doors

· insulation panels in some storage heaters

· bath panels

· central heating flues

· loose asbestos packing between floors and in partition walls

· floor tiles

Article Source: http://EzineArticles.com/7349301


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