While the risk is very low; taking a certain prescription drugs,
genericly known as Pioglitazone, for two years or more may double the
risk of bladder cancer. From September 1999 to September 2011 the FDA
received 121,715 reports of reactions related to the use of this drug.
Researchers learned the risk increased as the cumulative dosage
increased. (Source 2).
The
study was funded by the Canadian Institutes of Health Research and the
Canadian Foundation for Innovation. In the study, data was collected for
almost 116,000 patients who were treated for diabetes for a period of
21 years. During a 5-year follow-up, 470 patients were diagnosed with
bladder cancer. Not all these patients took Pioglitazone for diabetes.
However, among the patients who did, there was an 83 percent increase in
the relative risk of bladder cancer. In a broad spectrum of the United
Kingdom population, the rate of cancer for older adults is 73 cases per
100,000.
Putting the Pioglitazone bladder cancer rate into
perspective, the absolute risk was low with 89 cases among 100,000
people who took the drug during the five follow-up years. (Source 1).
While
the Pioglitazone cancer risk is considered low, in June 2011, there was
enough of a risk for the U.S. Food & Drug Administration to inform
the public that using Pioglitazone for more than one year may be
associated with an increased risk of bladder cancer. This information
was to be added to the Warnings and Precautions section of the
label for many name brand Pioglitazone drugs. The patient Medication
Guide for the above medicines was also to include information on bladder
cancer risk.
The FDA based their recommendation to inform the
public further on data from a planned five-year interim analysis of an
ongoing, 10-year epidemiological study. The 5-year results demonstrated
that although there was no overall increased risk of Pioglitazone
bladder cancer there was an increased risk of bladder cancer noted among
patients with the longest exposure to Pioglitazone medication and for
those patients exposed to the highest cumulative doses.
Concurrently,
France was conducting its own epidemiological study for Pioglitazone
medications and based on their findings, suspended the sale and use of
Pioglitazone medications. Germany made the recommendation to not
prescribe Pioglitazone to new type 2 diabetes patients.
Tuesday
What Is The Best Alternative Cancer Treatment?
NOTE: Before undergoing any type of treatment for a disease as
serious as cancer, please consult your physician. This article is not
meant to be taken as absolute medical advice. The information in this
article is designed to be educational and informational only. Please
consult a doctor/physician to discuss your treatment options further.
There are a surprising number of alternative cancer treatment options available these days. Each case of cancer is unique so it's extremely important to answer your doctor's questions so they can give you the best possible care for every type and stage of cancer from treatment of pre-cancerous conditions to Stage 4 cancer. Many alternative cancer treatments can also be used for cancer prevention.
An in-depth evaluation and subsequent laboratory tests by your doctor can indicate possible contributors to cancer and reveal baseline status. If there is exposure history, screening can be done to determine the presence of toxins in the body. Toxins such as heavy metals and pesticides can actually contribute to cancer growth. Testing for malignin can be done as well.
Many believe that the presence of malignin in the body is a marker for cancer. In this way, we can attempt to assess the effectiveness of cancer therapies through AMAS (anti-malignin antibody in serum) testing without exposing the patient to harmful radiation.
Nearly all alternative cancer treatments can be used in conjunction with standard chemotherapy and radiation or as stand alone cancer therapies. In addition to fighting cancer cells, these therapies often improve many other functions of the human body and can work to improve a patient's overall sense of wellness.
Another benefit to alternative cancer treatment is location. Every year, there are more and more doctors practicing alternative medicine. As a result, people can find treatment in places closer to home, with no need to travel to the US, Mexico, or Europe for treatment.
All About Artemisinin
Artemisinin is a chemical compound extracted from what is commonly known as the wormwood plant, Artemisia annua L. Wormwood extract contains a mechanism that selectively kills cancer cells while leaving normal cells intact. It does this by destroying cells that are abnormally high in iron and causing free radical destruction of the cell membranes. Normal cells don't store iron in such high concentrations. Cancer cells and parasites, however, do.
For centuries, Wormwood has been used as an effective treatment for malaria caused by parasites. Researchers at the National Cancer Institute's Developmental Therapeutic Program made the realization that artemisinin may also be effective not only for destroying parasites but also cancer cells, as they too store iron in high concentrations.
There are a surprising number of alternative cancer treatment options available these days. Each case of cancer is unique so it's extremely important to answer your doctor's questions so they can give you the best possible care for every type and stage of cancer from treatment of pre-cancerous conditions to Stage 4 cancer. Many alternative cancer treatments can also be used for cancer prevention.
An in-depth evaluation and subsequent laboratory tests by your doctor can indicate possible contributors to cancer and reveal baseline status. If there is exposure history, screening can be done to determine the presence of toxins in the body. Toxins such as heavy metals and pesticides can actually contribute to cancer growth. Testing for malignin can be done as well.
Many believe that the presence of malignin in the body is a marker for cancer. In this way, we can attempt to assess the effectiveness of cancer therapies through AMAS (anti-malignin antibody in serum) testing without exposing the patient to harmful radiation.
Nearly all alternative cancer treatments can be used in conjunction with standard chemotherapy and radiation or as stand alone cancer therapies. In addition to fighting cancer cells, these therapies often improve many other functions of the human body and can work to improve a patient's overall sense of wellness.
Another benefit to alternative cancer treatment is location. Every year, there are more and more doctors practicing alternative medicine. As a result, people can find treatment in places closer to home, with no need to travel to the US, Mexico, or Europe for treatment.
All About Artemisinin
Artemisinin is a chemical compound extracted from what is commonly known as the wormwood plant, Artemisia annua L. Wormwood extract contains a mechanism that selectively kills cancer cells while leaving normal cells intact. It does this by destroying cells that are abnormally high in iron and causing free radical destruction of the cell membranes. Normal cells don't store iron in such high concentrations. Cancer cells and parasites, however, do.
For centuries, Wormwood has been used as an effective treatment for malaria caused by parasites. Researchers at the National Cancer Institute's Developmental Therapeutic Program made the realization that artemisinin may also be effective not only for destroying parasites but also cancer cells, as they too store iron in high concentrations.
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